Expresión de búsqueda: TOR SERINE-THREONINE KINASES 
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Descriptor Inglés:   TOR Serine-Threonine Kinases 
Descriptor Español:   Serina-Treonina Quinasas TOR 
Descriptor Portugués:   Serina-Treonina Quinases TOR 
Sinónimos Inglés:   mTOR Serine-Threonine Kinases
TOR Kinases  
Categoría:   D08.811.913.696.620.682.700.931
D12.776.476.925
Definición Inglés:   A serine threonine kinase that controls a wide range of growth-related cellular processes. The protein is referred to as the target of RAPAMYCIN due to the discovery that SIROLIMUS (commonly known as rapamycin) forms an inhibitory complex with TACROLIMUS BINDING PROTEIN 1A that blocks the action of its enzymatic activity. 
Nota Histórica Inglés:   2011 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número del Registro:   54051 
Identificador Único:   D058570 

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